TEAD-IN-16
Product Specifications
UNSPSC Description
TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with the IC50 of 72.43 μM. TEAD-IN-16 plays an important role in cancer research[1].
Target Antigen
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tead-in-16.html
Smiles
COC1=C(COC2=CC=C(C=C2)C(F)(F)F)C=C(C(N)=O)C=C1
Molecular Weight
325.28
References & Citations
[1]Jongwan Kim, et al. Leveraging the Fragment Molecular Orbital and MM-GBSA Methods in Virtual Screening for the Discovery of Novel Non-Covalent Inhibitors Targeting the TEAD Lipid Binding Pocket. Int J Mol Sci. 2024 May 14;25(10):5358.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163732/TEAD-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163732/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7026429-01 0.02 mg
Recombinant Escherichia coli Glycerol-3-phosphate acyltransferase (plsY)
Ask
View Details MBS7026429-02 0.1 mg
Recombinant Escherichia coli Glycerol-3-phosphate acyltransferase (plsY)
Ask
View Details MBS7026429-03 5x 0.1 mg
Recombinant Escherichia coli Glycerol-3-phosphate acyltransferase (plsY)
Ask
View Details 
MBS1181007-01 0.05 mg (E-Coli)
Recombinant Neurospora crassa Flap endonuclease 1 (fen-1)
Ask
View Details MBS1181007-02 0.05 mg (Yeast)
Recombinant Neurospora crassa Flap endonuclease 1 (fen-1)
Ask
View Details