Polynucleotide kinase
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini[1].
Product Specifications
CAS Number
37211-65-7
UNSPSC
12352204
Hazard Statement
H334
Target
DNA/RNA Synthesis
Type
Enzyme
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/polynucleotide-kinase.html
Solubility
10 mM in DMSO
Smiles
[Polynucleotidekinase]
Precautions
H334
References & Citations
[1]Bernstein NK, et al. Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors. Anticancer Agents Med Chem. 2008 May;8 (4) :358-67.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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