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Polynucleotide kinase

Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini[1].

Product Specifications

CAS Number

37211-65-7

UNSPSC

12352204

Hazard Statement

H334

Target

DNA/RNA Synthesis

Type

Enzyme

Related Pathways

Cell Cycle/DNA Damage

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/polynucleotide-kinase.html

Solubility

10 mM in DMSO

Smiles

[Polynucleotidekinase]

Precautions

H334

References & Citations

[1]Bernstein NK, et al. Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors. Anticancer Agents Med Chem. 2008 May;8 (4) :358-67.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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