6-Oxolithocholic acid
Product Specifications
UNSPSC Description
6-Oxolithocholic acid is a bile acid metabolite derived from Lithocholic acid (HY-B0172). 6-Oxolithocholic acid has high cytotoxicity and can induce apoptosis, especially in hepatocytes. 6-Oxolithocholic acid can participate in the regulation of bile acid metabolism and synthesis and affect the metabolic pathway of cholesterol. 6-Oxolithocholic acid can be used to study the role of bile acids in health and disease, especially in the context of digestive and liver diseases[1].
Target Antigen
Apoptosis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/6-oxolithocholic-acid.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](CC([C@]1([H])C[C@@H](CC2)O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C
Molecular Weight
390.56
References & Citations
[1]Zimniak P, et al. Detoxification of lithocholic acid. Elucidation of the pathways of oxidative metabolism in rat liver microsomes[J]. Journal of lipid research, 1989, 30(6): 907-918.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W587530/6-Oxolithocholic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W587530/6-Oxolithocholic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2393-61-5
Available Sizes
Curated Selection
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