GPR41 modulator 1

GPR41 modulator 1 (compound 10ak) is a potent GPR41 modulator with an EC50 value of 0.679 µM. GPR41 modulator 1 shows agonistic modulator activity[1].

Product Specifications

CAS Number

[3050768-93-6]

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/gpr41-modulator-1.html

Smiles

FC1=CC(F)=CC(C2=CC=C(O2)C3C(C(NC4=C(C=CC=C4)C)=O)=C(NC5=C3C(CCC5)=O)C)=C1

Molecular Formula

C28H24F2N2O3

Molecular Weight

474.50

References & Citations

[1]Inuki S, et al. Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators. Bioorg Med Chem Lett. 2024 Jul 15;107:129758.