SCH 50911
SCH 50911, (+) - (S) -5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA (B) receptor antagonist, binds to GABA (B) receptor with IC50 of 1.1 μM. SCH 50911 antagonizes GABA (B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM[1].
Product Specifications
CAS Number
733717-87-8
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sch-50911.html
Purity
98.0
Solubility
H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C[C@H]1CNC(C)(C)CO1
Molecular Formula
C8H15NO3
Molecular Weight
173.21
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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