FFN 206 (dihydrochloride)

FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles[1].

Product Specifications

CAS Number

[1883548-88-6]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ffn-206-dihydrochloride.html

Purity

99.45

Solubility

10 mM in DMSO

Smiles

CNC1=CC=C2C(OC(C=C2CCN)=O)=C1.Cl.Cl

Molecular Formula

C12H16Cl2N2O2

Molecular Weight

291.17

References & Citations

[1]Gang Hu, et al. New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2) . ACS Chem Biol. 2013 Sep 20;8 (9) :1947-54.