L-Cysteic acid

L-Cysteic acid is the oxidation product of L-cystine. L-Cysteic acid is a substrate of GADCase/CADCaseII. L-Cysteic acid has high affinity with CADCase I (Km = 0.22 mM) . L-Cysteic acid is taken up by the synaptosome through a high affinity, Na+-dependent transport system[1][2].

Product Specifications

CAS Number

[498-40-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-cysteic-acid.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@H](C(O)=O)CS(=O)(O)=O

Molecular Formula

C3H7NO5S

Molecular Weight

169.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Wu JY. Purification and characterization of cysteic acid and cysteine sulfinic acid decarboxylase and L-glutamate decarboxylase from bovine brain. Proc Natl Acad Sci U S A. 1982 Jul;79 (14) :4270-4.|[2]Wilson DF, et al. Transport of cysteate by synaptosomes isolated from rat brain: evidence that it utilizes the same transporter as aspartate, glutamate, and cysteine sulfinate. J Neurochem. 1986 Oct;47 (4) :1091-7.