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Calpinactam

Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively[1].

Product Specifications

CAS Number

1205538-83-5

Product Name Alternative

FKI-4905

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/calpinactam.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC=N1)C(N[C@H](CCC(O)=O)C(N[C@H]([C@@H](C)CC)C(N[C@@H]2C(NCCCC2)=O)=O)=O)=O)=O)[C@@H](CC3=CC=CC=C3)N

Molecular Formula

C38H57N9O8

Molecular Weight

767.91

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Nobuhiro Koyama, et al.Calpinactam, a new anti-mycobacterial agent, produced by Mortierella alpina FKI-4905. J Antibiot (Tokyo) . 2010 Apr;63 (4) :183-6.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Microbial Metabolite

Available Sizes

Frequently Asked Questions

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