Human IGFBP-3 R / TMEM219 Protein, Fc Tag (MALS verified)
Human IGFBP-3 R, Fc Tag (IGR-H5259) is expressed from human 293 cells (HEK293) . It contains AA Ser 39 - Arg 204 (Accession # Q86XT9-1) .
Product Specifications
Background
IGFBP-3 R, also know as TMEM219, is a cell death receptor specific for IGFBP3. IGFBP-3R is expressed on the cell surface, interacts specifically with IGFBP-3 but not other IGFBP species. It activates initiator caspase-8, and mediates IGFBP-3-induced apoptosis in vitro and tumor suppression in vivo.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.3 kDa. The protein migrates as 58-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q86XT9-1
Expression Region
Ser 39 - Arg 204
Host
HEK293
Target
IGFBP-3 R
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
44.3 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IGR-H5259.pdf
Species
Human
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