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PDK1 allosteric modulator 1

PDK1 allosteric modulator 1 is a molecule targeting PDK1 with a binding affinity of 8 μM. PDK1 allosteric modulator 1 is able to bind to the PIF pocket of PDK1, potentially affecting the biological activity of this kinase[1].

Product Specifications

CAS Number

303134-93-2

UNSPSC

12352211

Hazard Statement

H315, H319

Target

PDK-1

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pdk1-allosteric-modulator-1.html

Purity

99.34

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(CN1C(SCCOC2=C(F)C=CC=C2)=NC3=C1C=CC=C3)O

Molecular Formula

C17H15FN2O3S

Molecular Weight

346.38

Precautions

H315, H319

References & Citations

[1]Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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