PC-Biotin-PEG4-NHS carbonate
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2055198-03-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pc-biotin-peg4-nhs-carbonate.html
Purity
97.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NCCOCCOCCOCCOCCC(NCC3=CC(C(OC(ON4C(CCC4=O)=O)=O)C)=C([N+]([O-])=O)C=C3)=O)=O)[H]
Molecular Formula
C35H50N6O14S
Molecular Weight
810.87
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Curated Selection
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