ZLN024 (hydrochloride)
ZLN024 hydrochloride is an AMPK allosteric activator. ZLN024 directly activates recombinant AMPK α1β1γ1, AMPK α2β1γ1, AMPK α1β2γ1 and AMPK α2β2γ1 heterotrimer with EC50s of 0.42 μM, 0.95 μM, 1.1 μM and 0.13 μM, respectively.
Product Specifications
CAS Number
[1883548-91-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ZLN024-hydrochloride.html
Concentration
10mM
Purity
98.51
Solubility
DMSO : ≥ 46 mg/mL|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CC1=CC=C(OCCSC2=NC=CC=N2)C(Br)=C1.[H]Cl
Molecular Formula
C13H14BrClN2OS
Molecular Weight
361.69
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPK α1β1γ1; AMPK α1β2γ1; AMPK α2β1γ1; AMPK α2β2γ1
Available Sizes
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