PD-1/PD-L1-IN-47
PD-1/PD-L1-IN-47 (MolPort-001-742-690) is a PH-selective PD-1/PD-L1 signaling pathway inhibitor with significant affinity for PD-L1 under acidic conditions and lower toxicity. PD-1/PD-L1-IN-47 can be used in the study of tumors[1].
Product Specifications
CAS Number
1137341-95-7
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-47.html
Smiles
CC(C1(CC(OC1)=O)O)CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)COC(/C=C/C3=CC(O)=C(C=C3)O)=O
Molecular Formula
C22H28O12
Molecular Weight
484.45
References & Citations
[1]McDowell RC, et al. Computational Approach for the Development of pH-Selective PD-1/PD-L1 Signaling Pathway Inhibition in Fight with Cancer. Cancers (Basel) . 2024 Jun 22;16 (13) :2295.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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