BAY-43-9695
BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261) [1].
Product Specifications
CAS Number
[233255-39-5]
UNSPSC
12352005
Target
CMV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bay-43-9695.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C)(CO)C)NC1=CC=C(NS(=O)(C2=C3C=CC=C(NC)C3=CC=C2)=O)C=C1
Molecular Formula
C22H25N3O4S
Molecular Weight
427.52
References & Citations
[1]McSharry JJ, et al., Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir. Antimicrob Agents Chemother. 2001 Oct;45 (10) :2925-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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