BAY-43-9695

BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261) [1].

Product Specifications

CAS Number

[233255-39-5]

UNSPSC

12352005

Target

CMV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bay-43-9695.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C)(CO)C)NC1=CC=C(NS(=O)(C2=C3C=CC=C(NC)C3=CC=C2)=O)C=C1

Molecular Formula

C22H25N3O4S

Molecular Weight

427.52

References & Citations

[1]McSharry JJ, et al., Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir. Antimicrob Agents Chemother. 2001 Oct;45 (10) :2925-7.