Sennidin B
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation [1][2].
Product Specifications
CAS Number
517-44-2
UNSPSC
12352005
Hazard Statement
H302
Target
Akt; GLUT; HCV
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sennidin-b.html
Purity
99.25
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(O)C=C(C(O)=O)C=C2[C@@]([C@]3([H])C4=CC(C(O)=O)=CC(O)=C4C(C5=C(O)C=CC=C35)=O)([H])C6=CC=CC(O)=C16
Molecular Formula
C30H18O10
Molecular Weight
538.46
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
GLUT4
Available Sizes
Frequently Asked Questions
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