α-Truxillic acid
α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities. α-Truxillic acid has no analgesic activity, but its derivatives bound to camphor fragments exhibit significant activity in the peripheral analgesic model (writhing test) [1][2].
Product Specifications
CAS Number
490-20-0
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alpha-truxillic-acid.html
Purity
99.93
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC([C@H]1[C@@H]([C@@H]([C@H]1C2=CC=CC=C2)C(O)=O)C3=CC=CC=C3)=O
Molecular Formula
C18H16O4
Molecular Weight
296.32
Precautions
H302, H312, H332
References & Citations
[1]Chi YM, et al. Antinociceptive activities of alpha-truxillic acid and beta-truxinic acid derivatives. Biol Pharm Bull. 2006 Mar;29 (3) :580-4.|[2]Sokolova A, et al. Synthesis and analgesic activity of new α-truxillic acid derivatives with monoterpenoid fragments[J]. Medicinal Chemistry Research, 2016, 25 (8) : 1608-1615.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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