Dihomo-γ-Linolenic acid methyl ester

Dihomo-γ-Linolenic acid methyl ester is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects[1][2].

Product Specifications

CAS Number

[21061-10-9]

Product Name Alternative

BAW2881

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dihomo-γ-linolenic-acid-methyl-ester.html

Concentration

312 mM * 50 μL in Ethanol

Purity

98.00

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(OC)=O

Molecular Formula

C21H36O2

Molecular Weight

320.51

Precautions

H225, H319

References & Citations

[1]Takai S, et al. Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice. J Atheroscler Thromb. 2009;16 (4) :480-489. |[2]Chutrakul C, et al. Metabolic engineering of long chain-polyunsaturated fatty acid biosynthetic pathway in oleaginous fungus for dihomo-gamma linolenic acid production. J Biotechnol. 2016;218:85-93.