P-gp inhibitor 1
P-gp inhibitor 1 is a novel inhibitor reversing P-glycoprotein-mediated multidrug resistance.
Product Specifications
CAS Number
2050747-49-2
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/P-gp_inhibitor_1.html
Purity
98.79
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
COC(C(OC)=C1)=CC2=C1CCN(C2)CCC3=CC=C(NC4=NC(C5=CC=NC=C5)=NC6=CC=CC=C46)C=C3
Molecular Formula
C32H31N5O2
Molecular Weight
517.62
References & Citations
[1]Qiu Q, et al. Design, Synthesis, and Pharmacological Characterization of N- (4- (2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2 (1H) yl) ethyl) phenyl) quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance. J Med Chem. 2017 Apr 27;60 (8) :3289-3302.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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