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Bovine neutrophil beta-defensin 12

Product Specifications

UNSPSC Description

Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus[1].

Target Antigen

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bovine-neutrophil-beta-defensin-12.html

Solubility

10 mM in DMSO

Smiles

O=C(CN)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N2C(C(N[C@H](C(NC(C(N[C@H](C(N3[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]5[C@@H](C)O)=O)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCSC)=O)CCC4)=O)C(C)C)=O)CCC3)=O)CSSC[C@H](NC6=O)C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC7=CNC8=CC=CC=C78)=O)CO)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCC2)=O)[C@H](CC)C)=O)CSSC[C@H](NC5=O)C(NC(C(NCC(NC(C(N9C(C(NC(C(NC%10CCCCN)=O)C(C)C)=O)CCC9)=O)CCCNC(N)=N)=O)=O)CC%11=CC=CC=C%11)=O)=O)C(C)C)=O)=O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)=O)CSSC[C@@H]6NC%10=O)=O)CO)=O)CC(C)C)=O)CCC1

Molecular Weight

4099.90

References & Citations

[1]Zimmermann GR, et al. Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins. Biochemistry. 1995 Oct 17;34(41):13663-71.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P5603/Bovine-neutrophil-beta-defensin-12-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P5603/

Clinical Information

No Development Reported

CAS Number

455257-02-0

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