Olmutinib (hydrochloride)
Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC[1][2].
Product Specifications
CAS Number
1842366-97-5
Product Name Alternative
HM61713 (hydrochloride) ; BI 1482694 (hydrochloride)
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/olmutinib-hydrochloride.html
Smiles
O=C(NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C=C3)=NC5=C2SC=C5)=CC=C1)C=C.Cl.Cl
Molecular Formula
C26H28Cl2N6O2S
Molecular Weight
559.51
References & Citations
[1]Kim ES, et al. Olmutinib: First Global Approval. Drugs. 2016 Jul;76 (11) :1153-7.|[2]Mohamed W. Attwa, et al. Detection and characterization of olmutinib reactive metabolites by LC‐MS/MS: Elucidation of bioactivation pathways. Journal of Separation science. 18 November 2019.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB3813-100 1x 100 µL
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL
Sign In for Pricing
View Details 
BNC682616-100 1x 100 µL
Cadherin 17 / LI Cadherin (Liver-Intestine Marker) (CDH17/2616), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
