WSB1 Degrader 1
WSB1 Degrader 1 is a poten and orally active WSB1 (WD repeat and SOCS box-containing 1) degrader. WSB1 Degrader 1 has anticancer metastatic effects[1].
Product Specifications
CAS Number
[2306039-66-5]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wsb1-degrader-1.html
Purity
99.81
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
NC1=NC(C2=CC=C(OC)C(C)=C2)=C(C3=CC=C(OC)C(C)=C3)C=C1
Molecular Formula
C21H22N2O2
Molecular Weight
334.41
Precautions
H315, H319
References & Citations
[1]Jinxin Che, et al. Discovery of 5,6-Bis (4-methoxy-3-methylphenyl) pyridin-2-amine as a WSB1 Degrader to Inhibit Cancer Cell Metastasis. J Med Chem. 2021 Jun 1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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