Isoxicam (Standard)
Isoxicam (Standard) is the analytical standard of Isoxicam. This product is intended for research and analytical applications. Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].
Product Specifications
CAS Number
34552-84-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
COX; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isoxicam-standard.html
Purity
99.58
Smiles
O=C(C1=C(O)C2=CC=CC=C2S(N1C)(=O)=O)NC3=NOC(C)=C3
Molecular Formula
C14H13N3O5S
Molecular Weight
335.34
Precautions
H315, H319, H335
References & Citations
[1]DiPasquale G, et al. The antiinflammatory properties of isoxicam (4-hydroxy-2methyl-N- (5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) . Agents Actions. 1975 Aug;5 (3) :256-63.|[2]Xu S, et al. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 2014 Mar 7;289 (10) :6799-808.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
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