EDTA-AM
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA. Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation[1][2].
Product Specifications
CAS Number
162303-59-5
Product Name Alternative
EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; Mitosis
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/edta-am.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C)OCOC(CN(CCN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=O
Molecular Formula
C22H32N2O16
Molecular Weight
580.49
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
OLFR187 Peptide - C-terminal region (AAP96614)