Lalistat 2
Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells [1][2][3].
Product Specifications
CAS Number
[1234569-09-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lalistat-2.html
Purity
99.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1CCCCC1)OC2=NSN=C2N3CCCCC3
Molecular Formula
C13H20N4O2S
Molecular Weight
296.40
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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