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Oxytocin (acetate)

Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma[1][2].

Product Specifications

CAS Number

[6233-83-6]

Product Name Alternative

α-Hypophamine (acetate) ; Oxytocic hormone (acetate)

UNSPSC

12352209

Hazard Statement

H302, H360, H413

Target

Endogenous Metabolite; Oxytocin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Oxytocin-acetate.html

Purity

99.66

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C([C@H](CSSC[C@@H](C(N[C@H](C1=O)CC2=CC=C(O)C=C2)=O)N)NC([C@@H](NC([C@@H](NC(C(N1)[C@@H](C)CC)=O)CCC(N)=O)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CC(C)C)C(NCC(N)=O)=O)=O.CC(O)=O

Molecular Formula

C45H70N12O14S2

Molecular Weight

1067.24

Precautions

H302, H360, H413

References & Citations

[1]Shivali Kohli, et al. Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats. Neuropsychopharmacology. 2019 Jan;44 (2) :295-305.|[2]C Sue Carter, et al. Is Oxytocin "Nature's Medicine"? Pharmacol Rev. 2020 Oct;72 (4) :829-861.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Citation 01

Behav Brain Res. 2025 May 8:485:115540.|Bioact Mater. 2023 Mar 15:26:337-352.|Bioorg Chem. 2025 Feb 1:156:108235.|Exp Eye Res. 2025 Feb 6:110269.|J Ethnopharmacol. 2019 Dec 5:245:112181.|Nat Struct Mol Biol. 2022 Mar;29 (3) :274-281.|Peptides. 2024 Nov 27:171323.|Signal Transduct Target Ther. 2023 Jan 2;8 (1) :3.|SSRN. 2023 Jun 19.|Transl Psychiatry. 2024 May 25;14 (1) :208.|ACS Appl Mater Interfaces. 2022 May 18;14 (19) :21822-21835.|Am J Reprod Immunol. 2024 Oct 15.|Biomed Pharmacother. 2025 Mar:184:117919.|CNS Neurosci Ther. 2025 Jul;31 (7) :e70511.|Evid Based Complement Alternat Med. 2020 May 23;2020:8607931.|Front Pharmacol. 2019 Nov 15;10:1380.|J Headache Pain. 2021 Jul 27;22 (1) :84.|Neuroendocrinology. 2023;113 (3) :343-360.|Neurosci Bull. 2025 Aug 6.|NPJ Biofilms Microbiomes. 2025 Jun 21;11 (1) :113.|Organogenesis. 2025 Dec;21 (1) :2460261.|Psychoneuroendocrinology. 2024 Oct:168:107138.|Sci Rep. 2020 Oct 2;10 (1) :16383.

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