Pirlindole

Pirlindole is a selective and reversible MAO-A inhibitor[1]. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) [2].

Product Specifications

CAS Number

[60762-57-4]

UNSPSC

12352005

Target

Enterovirus; Monoamine Oxidase

Type

Reference compound

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pirlindole.html

Purity

98.90

Solubility

10 mM in DMSO|DMSO : ≥ 5mg/mL

Smiles

CC1=CC2=C(C=C1)N3C4=C2CCCC4NCC3

Molecular Formula

C15H18N2

Molecular Weight

226.32

References & Citations

[1]Bruhwyler J, et al. Pirlindole: a selective reversible inhibitor of monoamine oxidase A. A review of its preclinical properties. Pharmacol Res. 1997 Jul;36 (1) :23-33. |[2]Ulferts R, et al. Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. Antimicrob Agents Chemother. 2016 Apr 22;60 (5) :2627-38.