Bis-propargyl-PEG6
Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates[1]. Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[400775-35-1]
Product Name Alternative
NSC144303
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bis-propargyl-peg6.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOCCOCCOCC#C
Molecular Formula
C18H30O7
Molecular Weight
358.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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