Milrinone
Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.
Product Specifications
CAS Number
78415-72-2
Product Name Alternative
Win 47203
UNSPSC
12352005
Hazard Statement
H317, H319
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Milrinone.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O
Molecular Formula
C12H9N3O
Molecular Weight
211.22
Precautions
H317, H319
References & Citations
[1]Santhosh KT, et al. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 Jul;163 (6) :1223-36.|[2]Hentschel T, et al. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan;106 (1) :124-31.|[3]Kishi T, et al. Effects of milrinone on left ventricular end-systolic pressure-volume relationship of rat hearts in situ. Clin Exp Pharmacol Physiol. 2001 Sep;28 (9) :737-42.|[4]Taylor MS, et al. Effect of milrinone on small mesenteric artery vasoconstriction: role of K (+) channels. Am J Physiol. 1999 Jul;277 (1 Pt 1) :G69-78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
PDE3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470026-500 1x 500 µL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741134-100 1x 100 µL
Mucin 5AC (MUC5AC) (MUC5AC/917 + 45M1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details