What is the catalog number for Recombinant Murine Interleukin-3 (rMuIL-3)?

The catalog number for Recombinant Murine Interleukin-3 (rMuIL-3) is orb1495010.

What sizes are available for Recombinant Murine Interleukin-3 (rMuIL-3)?

Recombinant Murine Interleukin-3 (rMuIL-3) is available in the following size(s): 1 mg, 2 µg, 10 µg.

How many pack sizes does Recombinant Murine Interleukin-3 (rMuIL-3) come in?

Recombinant Murine Interleukin-3 (rMuIL-3) is available in 3 different pack sizes.

Is Recombinant Murine Interleukin-3 (rMuIL-3) in stock?

Recombinant Murine Interleukin-3 (rMuIL-3) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Murine Interleukin-3 (rMuIL-3)

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.

Product Specifications

Source

Escherichia coli.

Field of Research

Immunology & Inflammation

Endotoxin

Less than 1EU/mg of rmIL-3 as determined by LAL method.

Purity

>98% by SDS-PAGE and HPLC analyses.

Bioactivity

The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is 2 x 107 units/mg.

Form

Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4.

Molecular Weight

Approximately 15.1 kDa globular protein containing 135 amino acid residues.

Storage Conditions

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

Notes

For research use only.

Applications Notes

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.