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Recombinant Human Thymosin Beta 4 (rHuTβ4)

Thymosin Beta 4 is a naturally occurring peptide. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ4 is not a growth factor; rather, it is a major actin regulating peptide. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue.

Product Specifications

Source

Escherichia coli.

Endotoxin

Less than 1EU/mg of rHuTβ4 as determined by LAL method.

Purity

>97% by SDS-PAGE and HPLC analyses.

Bioactivity

Data is not available.

Form

Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4.

Molecular Weight

Approximately 4.9 kDa, a single non-glycosylated polypeptide chain containing 43 amino acids.

Storage Conditions

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

Notes

For research use only.

Applications Notes

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

Preservative

Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4.

AA Sequence

SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES

Available Sizes

Frequently Asked Questions

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