O-Vanillin

O-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A) - and 4-hydroperoxycyclophosphamide-induced NF-κB activation[1][2].

Product Specifications

CAS Number

[148-53-8]

Product Name Alternative

3-Methoxysalicylaldehyde

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/o-vanillin.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=CC=CC(OC)=C1O

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Li Q, et, al. o-Vanillin, a promising antifungal agent, inhibits Aspergillus flavus by disrupting the integrity of cell walls and cell membranes. Appl Microbiol Biotechnol. 2021 Jun;105 (12) :5147-5158.|[2]Marton A, et, al. Vanillin Analogues o-Vanillin and 2,4,6-Trihydroxybenzaldehyde Inhibit NFĸB Activation and Suppress Growth of A375 Human Melanoma. Anticancer Res. 2016 Nov;36 (11) :5743-5750.