ALK5-IN-34
Product Specifications
UNSPSC Description
ALK5-IN-34 is an selective orally active activin receptor-like kinase (ALK) inhibitor. ALK5-IN-34 can inhibit the activity of ALK5-IN-34 with an IC50 value of ≤10 nM. ALK5-IN-34 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer[1].
Target Antigen
TGF-beta/Smad; TGF-β Receptor
Type
Reference compound
Related Pathways
Stem Cell/Wnt;TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-34.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=CC2=C(NC3=NC(NC4=CC=CC(N5CCOCC5)=C4)=NC=C3)C=NN=C12
Molecular Weight
413.48
References & Citations
[1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent. WO2022126133A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151289/ALK5-IN-34-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151289/ALK5-IN-34-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2785430-90-0
Available Sizes
Curated Selection
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