ALK5-IN-34
ALK5-IN-34 is an selective orally active activin receptor-like kinase (ALK) inhibitor. ALK5-IN-34 can inhibit the activity of ALK5-IN-34 with an IC50 value of ≤10 nM. ALK5-IN-34 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer[1].
Product Specifications
CAS Number
[2785430-90-0]
UNSPSC
12352005
Target
TGF-beta/Smad; TGF-β Receptor
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-34.html
Purity
98.21
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=CC2=C(NC3=NC(NC4=CC=CC(N5CCOCC5)=C4)=NC=C3)C=NN=C12
Molecular Formula
C23H23N7O
Molecular Weight
413.48
References & Citations
[1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent. WO2022126133A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALK5
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Monkey Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1) ELISA Kit
Monkey Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1) ELISA Kit
Monkey Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1) ELISA Kit