Recombinant Human Macrophage Colony Stimulating Factor (rHuM-CSF)
M-CSF, also known as CSF-1, is a four α helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.
Product Specifications
Source
Baculovirus infected Silkworm
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1EU/mg of rHuM-CSF as determined by LAL method.
Purity
>95% by SDS-PAGE and HPLC analyses.
Bioactivity
Form
Lyophilized from a 0.2mm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.
Molecular Weight
Approximately 42.0 kDa, a covalently linked homodimer, of two 21.0 kDa polypeptide monomers (1-149 amino acid of human M-CSF) .
Storage Conditions
Notes
For research use only.
Applications Notes
Preservative
Lyophilized from a 0.2mm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.
AA Sequence
Available Sizes
Frequently Asked Questions
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