What is the catalog number for Recombinant Human Interleukin-17F (rHuIL-17F)?

The catalog number for Recombinant Human Interleukin-17F (rHuIL-17F) is orb1494962.

What sizes are available for Recombinant Human Interleukin-17F (rHuIL-17F)?

Recombinant Human Interleukin-17F (rHuIL-17F) is available in the following size(s): 1 mg, 5 µg, 25 µg.

How many pack sizes does Recombinant Human Interleukin-17F (rHuIL-17F) come in?

Recombinant Human Interleukin-17F (rHuIL-17F) is available in 3 different pack sizes.

Is Recombinant Human Interleukin-17F (rHuIL-17F) in stock?

Recombinant Human Interleukin-17F (rHuIL-17F) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human Interleukin-17F (rHuIL-17F)

Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

Product Specifications

Source

Escherichia coli.

Field of Research

Immunology & Inflammation

Endotoxin

Less than 1EU/g of rHuIL-17F as determined by LAL method.

Purity

>95% by SDS-PAGE and HPLC analyses.

Bioactivity

Measured by its ability to induce IL-6 production by NHDF cells, it’s fully biologically active when compared to standard.

Form

Lyophilized from a 0.2m filtered concentrated solution in PBS, pH 7.4.

Molecular Weight

A disulfide-linked homodimer of 30.1kDa, consisting of two 133 amino acid polypeptide chains.

Storage Conditions

This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

Notes

For research use only.

Applications Notes

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.