Recombinant Human Melanoma Inhibitor Activity Protein 2 (rHuMIA-2)
MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3) -like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity.
Product Specifications
Source
Escherichia coli
Field of Research
Cancer Biology; Pharmacology & Drug Discovery
Endotoxin
Less than 1EU/μg of rHuMIA-2 as determined by LAL method.
Purity
>97% by SDS-PAGE and HPLC analyses.
Bioactivity
Data Not Available.
Form
Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
Molecular Weight
11.5 kDa, a single non-glycosylated polypeptide chain containing 101 amino acids.
Storage Conditions
Notes
For research use only.
Applications Notes
Preservative
Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
AA Sequence
MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L
Available Sizes
Frequently Asked Questions
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