Tau-aggregation-IN-3
Tau-aggregation-IN-3 (compound 9) a Tau protein aggregation inhibitor (TAI) . Tau-aggregation-IN-3 shows activity in cell-based aggregation inhibition experiments (EC50=4.816 μM) . Tau-aggregation-IN-3 can be used in Alzheimer's disease research[1].
Product Specifications
CAS Number
[3032869-59-0]
UNSPSC
12352005
Target
Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tau-aggregation-in-3.html
Solubility
10 mM in DMSO
Smiles
CN(S(C)(=O)=O)C1=NC(C(NCC2=NN=C(C3=CC=CC=C3)C2)=O)=CS1
Molecular Formula
C16H17N5O3S2
Molecular Weight
391.47
References & Citations
[1]Claude Michel Wischik, et al. Thiazole derivatives as tau aggregation inhibitors.WO2024061658A1.2023-09-08
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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