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Tau-aggregation-IN-3

Selected Variant

HY-161448

Size: 1 Each

Tau-aggregation-IN-3 (compound 9) a Tau protein aggregation inhibitor (TAI) . Tau-aggregation-IN-3 shows activity in cell-based aggregation inhibition experiments (EC50=4.816 μM) . Tau-aggregation-IN-3 can be used in Alzheimer's disease research[1].

Product Specifications

CAS Number

3032869-59-0

UNSPSC

12352005

Target

Tau Protein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tau-aggregation-in-3.html

Solubility

10 mM in DMSO

Smiles

CN(S(C)(=O)=O)C1=NC(C(NCC2=NN=C(C3=CC=CC=C3)C2)=O)=CS1

Molecular Formula

C16H17N5O3S2

Molecular Weight

391.47

References & Citations

[1]Claude Michel Wischik, et al. Thiazole derivatives as tau aggregation inhibitors.WO2024061658A1.2023-09-08

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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