Tau-aggregation-IN-3
Tau-aggregation-IN-3 (compound 9) a Tau protein aggregation inhibitor (TAI) . Tau-aggregation-IN-3 shows activity in cell-based aggregation inhibition experiments (EC50=4.816 μM) . Tau-aggregation-IN-3 can be used in Alzheimer's disease research[1].
Product Specifications
CAS Number
3032869-59-0
UNSPSC
12352005
Target
Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tau-aggregation-in-3.html
Solubility
10 mM in DMSO
Smiles
CN(S(C)(=O)=O)C1=NC(C(NCC2=NN=C(C3=CC=CC=C3)C2)=O)=CS1
Molecular Formula
C16H17N5O3S2
Molecular Weight
391.47
References & Citations
[1]Claude Michel Wischik, et al. Thiazole derivatives as tau aggregation inhibitors.WO2024061658A1.2023-09-08
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC881429-500 1x 500 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040525-100 1x 100 µL
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740669-500 1x 500 µL
P27 / KIP1 (SX53G8), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681170-500 1x 500 µL
Vimentin (VM1170), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680709-500 1x 500 µL
Human Kappa Light Chain (KLC709), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details