Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19 (rMuMIP-3b/CCL19)
Macrophage Inflammatory Protein-3 beta also called CCL19, ELC (EBI1 Ligand Chemokine), Exodus-3 is a reported β chemokine that binds specifically to the chemokine receptor CCR7 / EBI1 / BLR2. It is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells.
Product Specifications
Source
Escherichia coli.
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1EU/μg of rMuMIP-3b/CCL19 as determined by LAL method.
Purity
>95% by SDS-PAGE and HPLC analyses.
Bioactivity
Measured by its ability to chemoattract human CCR7 transfected BaF3 mouse proB cells. The ED50 for this effect is typically 3-15 ng/mL.
Form
Lyophilized from a 0.2m filtered concentrated solution in PBS, pH 7.4.
Molecular Weight
Approximately 9.2 kDa, a single non-glycosylated polypeptide chain containing 83 amino acids.
Storage Conditions
Notes
For research use only.
Applications Notes
Preservative
Lyophilized from a 0.2m filtered concentrated solution in PBS, pH 7.4.
AA Sequence
GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Available Sizes
Frequently Asked Questions
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