PfFAS-II inhibitor 1
PfFAS-II inhibitor 1 (Compound 3) is a Plasmodium falciparum type II fatty acid biosynthesis pathway (PfFAS-II) inhibitor, with an IC50 of 0.63 μM for PfFabI enzyme. PfFAS-II inhibitor 1 has antimalarial activity[1].
Product Specifications
CAS Number
1459704-68-7
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pffas-ii-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C=C1)C=C(OC3=CC=C(C=C3O)Cl)C=C2
Molecular Formula
C15H9ClO4
Molecular Weight
288.68
References & Citations
[1]Belluti F, et al. Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI) . J Med Chem. 2013 Oct 10;56 (19) :7516-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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