What is the catalog number for RecombinantTNF-α, Human?

The catalog number for RecombinantTNF-α, Human is orb1494766.

What sizes are available for RecombinantTNF-α, Human?

RecombinantTNF-α, Human is available in the following size(s): 1 mg, 10 µg, 50 µg.

How many pack sizes does RecombinantTNF-α, Human come in?

RecombinantTNF-α, Human is available in 3 different pack sizes.

Is RecombinantTNF-α, Human in stock?

RecombinantTNF-α, Human is currently made to order / not held in immediate stock. Contact us for lead time.

RecombinantTNF-α, Human

Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha (TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease.Recombinant Human Tumor Necrosis Factor-alpha (TNF-α) produced in E.coli is a single non-glycosylated polypeptide chain containing 157 amino acids. A fully biologically active molecule, rhTNF-α has a molecular mass of 17.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

Product Specifications

Product Name Alternative

TNF-alpha, TNF-α; Tumornecrosis factor ligand super family member 2, TNF-a; TNFa, Cachectin, DIF, TNFA, TNFSF 2

Source

Escherichia coli.

Endotoxin

Less than 0.2 EU/μg determined by LAL test.

Purity

> 98% as analyzed by SDS-PAGE and HPLC.

Bioactivity

ED50 3.3 x 10ˆ7 units/mg.

Form

Lyophilized after extensive dialysis against PBS.

Molecular Weight

17.3 kDa, observed by reducing SDS-PAGE.

Storage Conditions

Lyophilized recombinant Human Tumor Necrosis Factor-alpha (TNF-α), remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human TNF-α should be stable up to 1 week at 4°C or up to 3 months at -20°C.

Notes

For research use only.

Applications Notes

Reconstituted in ddH2O or PBS at 100 μg/ml.

Preservative

Lyophilized after extensive dialysis against PBS.

AA Sequence

VRS SSRTPSDKPV AHVVANPQAE GQLQWLNRRA NALLANGVEL RDNQLVVPSE GLYLIYSQVL FKGQGCPSTH VLLTHTISRI AVSYQTKVNL LSAIKSPCQR ETPEGAEAKP WYEPIYLGGV FQLEKGDRLS AEINRPDYLD FAESGQVYFG IIAL