What is the catalog number for RecombinantPDGF-DD, Human?

The catalog number for RecombinantPDGF-DD, Human is orb1494670.

What sizes are available for RecombinantPDGF-DD, Human?

RecombinantPDGF-DD, Human is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does RecombinantPDGF-DD, Human come in?

RecombinantPDGF-DD, Human is available in 2 different pack sizes.

Is RecombinantPDGF-DD, Human in stock?

RecombinantPDGF-DD, Human is currently made to order / not held in immediate stock. Contact us for lead time.

RecombinantPDGF-DD, Human

PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.

Product Specifications

Product Name Alternative

Platelet-derived growth factor D, IEGF, SCDGFB

Source

CHO

Endotoxin

< 0.2 EU/μg, determined by LAL method.

Purity

> 95% as analyzed by SDS-PAGE.

Bioactivity

ED50 < 5 μg/ml, measured in a cell proliferation assay using 3T3 cells.

Form

Lyophilized after extensive dialysis against PBS.

Molecular Weight

19-21 kDa, observed by reducing SDS-PAGE.

Storage Conditions

Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4°C or up to 2 months at -20°C.