β-Glucuronidase-IN-1
β-Glucuronidase-IN-1 is a potent, selective, uncompetitive, and orally active E. coli bacterial β-glucuronidase inhibitor, exhibiting an IC50 and a Ki of 283 nM and 164 nM, respectively[1].
Product Specifications
CAS Number
484006-66-8
UNSPSC
12352005
Target
Bacterial; β-glucuronidase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/β-glucuronidase-in-1.html
Purity
98.21
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
S=C(NC1=CC=C(OCC)C=C1)N(CC2=CC3=C(NC2=O)C(C)=CC(C)=C3)CCO
Molecular Formula
C23H27N3O3S
Molecular Weight
425.54
References & Citations
[1]Wallace BD, et al. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.Science. 2010 Nov 5;330 (6005) :831-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MAGE A1 (MA454), CF488A conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF770 conjugate, 0.1mg/mL
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
