β-Glucuronidase-IN-1
β-Glucuronidase-IN-1 is a potent, selective, uncompetitive, and orally active E. coli bacterial β-glucuronidase inhibitor, exhibiting an IC50 and a Ki of 283 nM and 164 nM, respectively[1].
Product Specifications
CAS Number
[484006-66-8]
UNSPSC
12352005
Target
Bacterial; β-glucuronidase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/β-glucuronidase-in-1.html
Purity
98.21
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
S=C(NC1=CC=C(OCC)C=C1)N(CC2=CC3=C(NC2=O)C(C)=CC(C)=C3)CCO
Molecular Formula
C23H27N3O3S
Molecular Weight
425.54
References & Citations
[1]Wallace BD, et al. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.Science. 2010 Nov 5;330 (6005) :831-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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