Ravuconazole-d4
Ravuconazole-d4 is the deuterium labeled Ravuconazole. Ravuconazole (BMS-207147) is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi[1][2].
Product Specifications
CAS Number
1329499-27-5
UNSPSC
12352005
Target
Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
[C@@]([C@@H](C)C1=NC(=CS1)C2=C(C(=C(C#N)C(=C2[2H])[2H])[2H])[2H])(CN3C=NC=N3)(O)C4=C(F)C=C(F)C=C4
Molecular Formula
C22H13D4F2N5OS
Molecular Weight
441.49
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hata K, et al. In vitro and in vivo antifungal activities of ER-30346, a novel oral triazole with a broad antifungal spectrum.Antimicrob Agents Chemother. 1996 Oct;40 (10) :2237-42.|[3]Fung-Tomc JC, et al. In vitro activity of a new oral triazole, BMS-207147 (ER-30346) Antimicrob Agents Chemother. 1998 Feb;42 (2) :313-8.|[4]Hata K, et al. Efficacy of ER-30346, a novel oral triazole antifungal agent, in experimental models of aspergillosis, candidiasis, and cryptococcosis.Antimicrob Agents Chemother. 1996 Oct;40 (10) :2243-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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