Mizoribine
Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant[1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively[2].
Product Specifications
CAS Number
50924-49-7
Product Name Alternative
NSC 289637; HE 69
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H360
Target
Antibiotic; HCV; Parasite; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Mizoribine.html
Purity
99.99
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(O)=C(C(N)=O)N=C2)O1
Molecular Formula
C9H13N3O6
Molecular Weight
259.22
Precautions
H315, H319, H335, H360
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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