NCAM-1/CD56, Human (HEK293, His, solution)

Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His, solution) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

NCAM-1/CD56 Protein, Human (HEK293, His, solution), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/ncam-1-cd56-protein-human-603a-a-hek293-his.html

Purity

97.60

Molecular Formula

4684 (Gene_ID) P13591-3 (L20-P603) (Accession)

Molecular Weight

Approximately 66.1 kDa

References & Citations

[1]Overexpression of murine Pax3 increases NCAM polysialylation in a human medulloblastoma cell line. J Biol Chem. 2000 Jul 28;275 (30) :23259-66.|[2]Angata K, et al. Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III. J Biol Chem. 2000 Jun 16;275 (24) :18594-601.