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NH2-C6-NH-Boc

NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1].

Product Specifications

CAS Number

51857-17-1

UNSPSC

12352211

Hazard Statement

H314

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh2-c6-nh-boc.html

Purity

99.92

Solubility

Ethanol : 100 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)NCCCCCCN

Molecular Formula

C11H24N2O2

Molecular Weight

216.32

Precautions

H314

References & Citations

[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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