NH2-C6-NH-Boc
NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1].
Product Specifications
CAS Number
[51857-17-1]
UNSPSC
12352211
Hazard Statement
H314
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-c6-nh-boc.html
Purity
99.92
Solubility
Ethanol : 100 mg/mL (ultrasonic)
Smiles
O=C(OC(C)(C)C)NCCCCCCN
Molecular Formula
C11H24N2O2
Molecular Weight
216.32
Precautions
H314
References & Citations
[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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