2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
Product Specifications
UNSPSC Description
2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan (HY-13631). 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody[1].
Target Antigen
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-msp-5-ha-ggfg-nh-ch2-o-ch2-co-exatecan.html
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O
Molecular Weight
1091.13
References & Citations
[1]Cai JQ, et al. Antibody against her3, conjugate and use thereof. WO2023143263A1. 2023-08-03.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157813/2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157813/2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2964536-59-0
Available Sizes
Curated Selection
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